How has critique and skepticism been integrated or excluded in medicine? This event, part of our Institute's Colloquium 2021–22 series Trusting Science, addresses this question through two short presentations and a discussion between the historian Caitjan Gainty, who runs the Wellcome-funded “Healthy Scepticism” project at King’s College London, and the sociologist Ariane Hanemaayer, author of The Impossible Clinic: A Critical Sociology of Evidence-based Medicine. They address how historical and sociological perspectives on healthcare discontent help to situate the relationship between the role(s) of the skeptic and the preservation of trust in the medical system.