Based on Thomas’s recently published book, Science and Religion in India: Beyond Disenchantment (London: Routledge, 2021), this talk will address some of the emerging questions and concerns in Science and Technology Studies, and laboratory ethnography. The talk explores how caste and caste identities shape scientific culture in India. It will discuss how the notions of merit and passion for doing science was reinscribed and calibrated to denote the alleged castelessness and objectivity in science. The apparent castelessness and claims of objectivity among scientists co-existed with a significant interest in caste genealogies and family origins, and their preferences for distinct food habits and taste in cultural expressions. The talk will discuss in detail the ways in which the conversion of caste as culture normalised various caste-cultural practices among Indian scientists and preserved the image of science as Brahmins’ vocation.